The alveolate translation initiation factor 4E family reveals a custom toolkit for translational control in core dinoflagellates
Identifieur interne : 000065 ( Main/Exploration ); précédent : 000064; suivant : 000066The alveolate translation initiation factor 4E family reveals a custom toolkit for translational control in core dinoflagellates
Auteurs : Grant D. Jones [États-Unis] ; Ernest P. Williams [États-Unis] ; Allen R. Place [États-Unis] ; Rosemary Jagus [États-Unis] ; Tsvetan R. Bachvaroff [États-Unis]Source :
- BMC Evolutionary Biology [ 1471-2148 ] ; 2015.
Abstract
Dinoflagellates are eukaryotes with unusual cell biology and appear to rely on translational rather than transcriptional control of gene expression. The eukaryotic translation initiation factor 4E (eIF4E) plays an important role in regulating gene expression because eIF4E binding to the mRNA cap is a control point for translation. eIF4E is part of an extended, eukaryote-specific family with different members having specific functions, based on studies of model organisms. Dinoflagellate eIF4E diversity could provide a mechanism for dinoflagellates to regulate gene expression in a post-transcriptional manner. Accordingly, eIF4E family members from eleven core dinoflagellate transcriptomes were surveyed to determine the diversity and phylogeny of the eIF4E family in dinoflagellates and related lineages including apicomplexans, ciliates and heterokonts.
The survey uncovered eight to fifteen (on average eleven) different eIF4E family members in each core dinoflagellate species. The eIF4E family members from heterokonts and dinoflagellates segregated into three clades, suggesting at least three eIF4E cognates were present in their common ancestor. However, these three clades are distinct from the three previously described eIF4E classes, reflecting diverse approaches to a central eukaryotic function. Heterokonts contain four clades, ciliates two and apicomplexans only a single recognizable eIF4E clade. In the core dinoflagellates, the three clades were further divided into nine sub-clades based on the phylogenetic analysis and species representation. Six of the sub-clades included at least one member from all eleven core dinoflagellate species, suggesting duplication in their shared ancestor. Conservation within sub-clades varied, suggesting different selection pressures.
Phylogenetic analysis of eIF4E in core dinoflagellates revealed complex layering of duplication and conservation when compared to other eukaryotes. Our results suggest that the diverse eIF4E family in core dinoflagellates may provide a toolkit to enable selective translation as a strategy for controlling gene expression in these enigmatic eukaryotes.
The online version of this article (doi:10.1186/s12862-015-0301-9) contains supplementary material, which is available to authorized users.
Url:
DOI: 10.1186/s12862-015-0301-9
PubMed: 25886308
PubMed Central: 4330643
Affiliations:
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Jones</name><affiliation wicri:level="3"><nlm:aff id="Aff1">Institute of Marine and Environmental Technology, University of Maryland Center for Environmental Science, Baltimore, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute of Marine and Environmental Technology, University of Maryland Center for Environmental Science, Baltimore</wicri:regionArea><placeName><settlement type="city">Baltimore</settlement><region type="state">Maryland</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="Aff2">University of Maryland, Baltimore, Graduate School, Baltimore, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Maryland, Baltimore, Graduate School, Baltimore</wicri:regionArea><placeName><settlement type="city">Baltimore</settlement><region type="state">Maryland</region></placeName><orgName type="university">Université du Maryland</orgName></affiliation></author><author><name sortKey="Williams, Ernest P" sort="Williams, Ernest P" uniqKey="Williams E" first="Ernest P" last="Williams">Ernest P. Williams</name><affiliation wicri:level="3"><nlm:aff id="Aff1">Institute of Marine and Environmental Technology, University of Maryland Center for Environmental Science, Baltimore, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute of Marine and Environmental Technology, University of Maryland Center for Environmental Science, Baltimore</wicri:regionArea><placeName><settlement type="city">Baltimore</settlement><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Place, Allen R" sort="Place, Allen R" uniqKey="Place A" first="Allen R" last="Place">Allen R. Place</name><affiliation wicri:level="3"><nlm:aff id="Aff1">Institute of Marine and Environmental Technology, University of Maryland Center for Environmental Science, Baltimore, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute of Marine and Environmental Technology, University of Maryland Center for Environmental Science, Baltimore</wicri:regionArea><placeName><settlement type="city">Baltimore</settlement><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Jagus, Rosemary" sort="Jagus, Rosemary" uniqKey="Jagus R" first="Rosemary" last="Jagus">Rosemary Jagus</name><affiliation wicri:level="3"><nlm:aff id="Aff1">Institute of Marine and Environmental Technology, University of Maryland Center for Environmental Science, Baltimore, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute of Marine and Environmental Technology, University of Maryland Center for Environmental Science, Baltimore</wicri:regionArea><placeName><settlement type="city">Baltimore</settlement><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Bachvaroff, Tsvetan R" sort="Bachvaroff, Tsvetan R" uniqKey="Bachvaroff T" first="Tsvetan R" last="Bachvaroff">Tsvetan R. Bachvaroff</name><affiliation wicri:level="3"><nlm:aff id="Aff1">Institute of Marine and Environmental Technology, University of Maryland Center for Environmental Science, Baltimore, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute of Marine and Environmental Technology, University of Maryland Center for Environmental Science, Baltimore</wicri:regionArea><placeName><settlement type="city">Baltimore</settlement><region type="state">Maryland</region></placeName></affiliation></author></analytic><series><title level="j">BMC Evolutionary Biology</title><idno type="eISSN">1471-2148</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Background</title><p>Dinoflagellates are eukaryotes with unusual cell biology and appear to rely on translational rather than transcriptional control of gene expression. The eukaryotic translation initiation factor 4E (eIF4E) plays an important role in regulating gene expression because eIF4E binding to the mRNA cap is a control point for translation. eIF4E is part of an extended, eukaryote-specific family with different members having specific functions, based on studies of model organisms. Dinoflagellate eIF4E diversity could provide a mechanism for dinoflagellates to regulate gene expression in a post-transcriptional manner. Accordingly, eIF4E family members from eleven core dinoflagellate transcriptomes were surveyed to determine the diversity and phylogeny of the eIF4E family in dinoflagellates and related lineages including apicomplexans, ciliates and heterokonts.</p></sec><sec><title>Results</title><p>The survey uncovered eight to fifteen (on average eleven) different eIF4E family members in each core dinoflagellate species. The eIF4E family members from heterokonts and dinoflagellates segregated into three clades, suggesting at least three eIF4E cognates were present in their common ancestor. However, these three clades are distinct from the three previously described eIF4E classes, reflecting diverse approaches to a central eukaryotic function. Heterokonts contain four clades, ciliates two and apicomplexans only a single recognizable eIF4E clade. In the core dinoflagellates, the three clades were further divided into nine sub-clades based on the phylogenetic analysis and species representation. Six of the sub-clades included at least one member from all eleven core dinoflagellate species, suggesting duplication in their shared ancestor. Conservation within sub-clades varied, suggesting different selection pressures.</p></sec><sec><title>Conclusions</title><p>Phylogenetic analysis of eIF4E in core dinoflagellates revealed complex layering of duplication and conservation when compared to other eukaryotes. Our results suggest that the diverse eIF4E family in core dinoflagellates may provide a toolkit to enable selective translation as a strategy for controlling gene expression in these enigmatic eukaryotes.</p></sec><sec><title>Electronic supplementary material</title><p>The online version of this article (doi:10.1186/s12862-015-0301-9) contains supplementary material, which is available to authorized users.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Anderson, Dm" uniqKey="Anderson D">DM Anderson</name></author><author><name sortKey="Alpermann, Tj" uniqKey="Alpermann T">TJ Alpermann</name></author><author><name sortKey="Cembella, Ad" uniqKey="Cembella A">AD Cembella</name></author><author><name sortKey="Collos, Y" uniqKey="Collos Y">Y Collos</name></author><author><name sortKey="Masseret, E" uniqKey="Masseret E">E Masseret</name></author><author><name sortKey="Montresor, M" uniqKey="Montresor M">M Montresor</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Holmes, Mj" uniqKey="Holmes M">MJ Holmes</name></author><author><name sortKey="Brust, A" uniqKey="Brust A">A Brust</name></author><author><name sortKey="Lewis, Rj" uniqKey="Lewis R">RJ Lewis</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Spector, Dl" uniqKey="Spector D">DL Spector</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lin, S" uniqKey="Lin S">S Lin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wisecaver, Jh" uniqKey="Wisecaver J">JH Wisecaver</name></author><author><name sortKey="Hackett, Jd" uniqKey="Hackett J">JD Hackett</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shoguchi, E" uniqKey="Shoguchi E">E Shoguchi</name></author><author><name sortKey="Shinzato, C" uniqKey="Shinzato C">C Shinzato</name></author><author><name sortKey="Kawashima, T" uniqKey="Kawashima T">T Kawashima</name></author><author><name sortKey="Gyoja, F" uniqKey="Gyoja F">F Gyoja</name></author><author><name sortKey="Mungpakdee, S" uniqKey="Mungpakdee S">S Mungpakdee</name></author><author><name sortKey="Koyanagi, R" uniqKey="Koyanagi R">R Koyanagi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bachvaroff, Tr" uniqKey="Bachvaroff T">TR Bachvaroff</name></author><author><name sortKey="Concepcion, Gt" uniqKey="Concepcion G">GT Concepcion</name></author><author><name sortKey="Rogers, Cr" uniqKey="Rogers C">CR Rogers</name></author><author><name sortKey="Delwiche, Cf" uniqKey="Delwiche C">CF Delwiche</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bachvaroff, Tr" uniqKey="Bachvaroff T">TR Bachvaroff</name></author><author><name sortKey="Place, Ar" uniqKey="Place A">AR Place</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hiller, Rg" uniqKey="Hiller R">RG Hiller</name></author><author><name sortKey="Wrench, Pm" uniqKey="Wrench P">PM Wrench</name></author><author><name sortKey="Sharples, Fp" uniqKey="Sharples F">FP Sharples</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kim, S" uniqKey="Kim S">S Kim</name></author><author><name sortKey="Bachvaroff, Tr" uniqKey="Bachvaroff T">TR Bachvaroff</name></author><author><name sortKey="Handy, Sm" uniqKey="Handy S">SM Handy</name></author><author><name sortKey="Delwiche, Cf" uniqKey="Delwiche C">CF Delwiche</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Reichman, J" uniqKey="Reichman J">J Reichman</name></author><author><name sortKey="Wilcox, T" uniqKey="Wilcox T">T Wilcox</name></author><author><name sortKey="Vize, P" uniqKey="Vize P">P Vize</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rowan, R" uniqKey="Rowan R">R Rowan</name></author><author><name sortKey="Whitney, Sm" uniqKey="Whitney S">SM Whitney</name></author><author><name sortKey="Fowler, A" uniqKey="Fowler A">A Fowler</name></author><author><name sortKey="Yellowlees, D" uniqKey="Yellowlees D">D Yellowlees</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhang, H" uniqKey="Zhang H">H Zhang</name></author><author><name sortKey="Hou, Y" uniqKey="Hou Y">Y Hou</name></author><author><name sortKey="Lin, S" uniqKey="Lin S">S Lin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Le, Qh" uniqKey="Le Q">QH Le</name></author><author><name sortKey="Markovic, P" uniqKey="Markovic P">P Markovic</name></author><author><name sortKey="Hastings, Jw" uniqKey="Hastings J">JW Hastings</name></author><author><name sortKey="Jovine, Rv" uniqKey="Jovine R">RV Jovine</name></author><author><name sortKey="Morse, D" uniqKey="Morse D">D Morse</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Valiadi, M" uniqKey="Valiadi M">M Valiadi</name></author><author><name sortKey="Iglesias Rodriguez, Md" uniqKey="Iglesias Rodriguez M">MD Iglesias-Rodriguez</name></author><author><name sortKey="Amorim, A" uniqKey="Amorim A">A Amorim</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Liu, L" uniqKey="Liu L">L Liu</name></author><author><name sortKey="Hastings, J" uniqKey="Hastings J">J Hastings</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Liu, L" uniqKey="Liu L">L Liu</name></author><author><name sortKey="Wilson, T" uniqKey="Wilson T">T Wilson</name></author><author><name sortKey="Hastings, Jw" uniqKey="Hastings J">JW Hastings</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Guillebault, D" uniqKey="Guillebault D">D Guillebault</name></author><author><name sortKey="Sasorith, S" uniqKey="Sasorith S">S Sasorith</name></author><author><name sortKey="Derelle, E" uniqKey="Derelle E">E Derelle</name></author><author><name sortKey="Wurtz, Jm" uniqKey="Wurtz J">JM Wurtz</name></author><author><name sortKey="Lozano, Jc" uniqKey="Lozano J">JC Lozano</name></author><author><name sortKey="Bingham, S" uniqKey="Bingham S">S Bingham</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Morse, D" uniqKey="Morse D">D Morse</name></author><author><name sortKey="Milos, Pm" uniqKey="Milos P">PM Milos</name></author><author><name sortKey="Roux, E" uniqKey="Roux E">E Roux</name></author><author><name sortKey="Hastings, Jw" uniqKey="Hastings J">JW Hastings</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Toulza, E" uniqKey="Toulza E">E Toulza</name></author><author><name sortKey="Shin, Ms" uniqKey="Shin M">MS Shin</name></author><author><name sortKey="Blanc, G" uniqKey="Blanc G">G Blanc</name></author><author><name sortKey="Audic, S" uniqKey="Audic S">S Audic</name></author><author><name sortKey="Laabir, M" uniqKey="Laabir M">M Laabir</name></author><author><name sortKey="Collos, Y" uniqKey="Collos Y">Y Collos</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lidie, Kb" uniqKey="Lidie K">KB Lidie</name></author><author><name sortKey="Ryan, Jc" uniqKey="Ryan J">JC Ryan</name></author><author><name sortKey="Barbier, M" uniqKey="Barbier M">M Barbier</name></author><author><name sortKey="Van Dolah, Fm" uniqKey="Van Dolah F">FM Van Dolah</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Morey, Js" uniqKey="Morey J">JS Morey</name></author><author><name sortKey="Monroe, Ea" uniqKey="Monroe E">EA Monroe</name></author><author><name sortKey="Kinney, Al" uniqKey="Kinney A">AL Kinney</name></author><author><name sortKey="Beal, M" uniqKey="Beal M">M Beal</name></author><author><name sortKey="Johnson, Jg" uniqKey="Johnson J">JG Johnson</name></author><author><name sortKey="Hitchcock, Gl" uniqKey="Hitchcock G">GL Hitchcock</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lowe, Cd" uniqKey="Lowe C">CD Lowe</name></author><author><name sortKey="Mello, Lv" uniqKey="Mello L">LV Mello</name></author><author><name sortKey="Samatar, N" uniqKey="Samatar N">N Samatar</name></author><author><name sortKey="Martin, Le" uniqKey="Martin L">LE Martin</name></author><author><name sortKey="Montagnes, Dj" uniqKey="Montagnes D">DJ Montagnes</name></author><author><name sortKey="Watts, Pc" uniqKey="Watts P">PC Watts</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Moustafa, A" uniqKey="Moustafa A">A Moustafa</name></author><author><name sortKey="Evans, An" uniqKey="Evans A">AN Evans</name></author><author><name sortKey="Kulis, Dm" uniqKey="Kulis D">DM Kulis</name></author><author><name sortKey="Hackett, Jd" uniqKey="Hackett J">JD Hackett</name></author><author><name sortKey="Erdner, Dl" uniqKey="Erdner D">DL Erdner</name></author><author><name sortKey="Anderson, Dm" uniqKey="Anderson D">DM Anderson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yang, I" uniqKey="Yang I">I Yang</name></author><author><name sortKey="John, U" uniqKey="John U">U John</name></author><author><name sortKey="Beszteri, S" uniqKey="Beszteri S">S Beszteri</name></author><author><name sortKey="Glockner, G" uniqKey="Glockner G">G Glockner</name></author><author><name sortKey="Krock, B" uniqKey="Krock B">B Krock</name></author><author><name sortKey="Goesmann, A" uniqKey="Goesmann A">A Goesmann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Roy, S" uniqKey="Roy S">S Roy</name></author><author><name sortKey="Morse, D" uniqKey="Morse D">D Morse</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lidie, Kb" uniqKey="Lidie K">KB Lidie</name></author><author><name sortKey="Van Dolah, Fm" uniqKey="Van Dolah F">FM Van Dolah</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhang, J" uniqKey="Zhang J">J Zhang</name></author><author><name sortKey="Hou, Y" uniqKey="Hou Y">Y Hou</name></author><author><name sortKey="Miranda, L" uniqKey="Miranda L">L Miranda</name></author><author><name sortKey="Campbell, D" uniqKey="Campbell D">D Campbell</name></author><author><name sortKey="Sturm, N" uniqKey="Sturm N">N Sturm</name></author><author><name sortKey="Gaasterland, T" uniqKey="Gaasterland T">T Gaasterland</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jagus, R" uniqKey="Jagus R">R Jagus</name></author><author><name sortKey="Bachvaroff, Tr" uniqKey="Bachvaroff T">TR Bachvaroff</name></author><author><name sortKey="Joshi, B" uniqKey="Joshi B">B Joshi</name></author><author><name sortKey="Place, Ar" uniqKey="Place A">AR Place</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Marcotrigiano, J" uniqKey="Marcotrigiano J">J Marcotrigiano</name></author><author><name sortKey="Gingras, Ac" uniqKey="Gingras A">AC Gingras</name></author><author><name sortKey="Sonenberg, N" uniqKey="Sonenberg N">N Sonenberg</name></author><author><name sortKey="Burley, Sk" uniqKey="Burley S">SK Burley</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Matsuo, H" uniqKey="Matsuo H">H Matsuo</name></author><author><name sortKey="Li, H" uniqKey="Li H">H Li</name></author><author><name sortKey="Mcguire, Am" uniqKey="Mcguire A">AM McGuire</name></author><author><name sortKey="Fletcher, Cm" uniqKey="Fletcher C">CM Fletcher</name></author><author><name sortKey="Gingras, Ac" uniqKey="Gingras A">AC Gingras</name></author><author><name sortKey="Sonenberg, N" uniqKey="Sonenberg N">N Sonenberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Joshi, B" uniqKey="Joshi B">B Joshi</name></author><author><name sortKey="Lee, K" uniqKey="Lee K">K Lee</name></author><author><name sortKey="Maeder, Dl" uniqKey="Maeder D">DL Maeder</name></author><author><name sortKey="Jagus, R" uniqKey="Jagus R">R Jagus</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kamenska, A" uniqKey="Kamenska A">A Kamenska</name></author><author><name sortKey="Simpson, C" uniqKey="Simpson C">C Simpson</name></author><author><name sortKey="Standart, N" uniqKey="Standart N">N Standart</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hernandez, G" uniqKey="Hernandez G">G Hernandez</name></author><author><name sortKey="Altmann, M" uniqKey="Altmann M">M Altmann</name></author><author><name sortKey="Sierra, Jm" uniqKey="Sierra J">JM Sierra</name></author><author><name sortKey="Urlaub, H" uniqKey="Urlaub H">H Urlaub</name></author><author><name sortKey="Diez Del Corral, R" uniqKey="Diez Del Corral R">R Diez del Corral</name></author><author><name sortKey="Schwartz, P" uniqKey="Schwartz P">P Schwartz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Aitken, Ce" uniqKey="Aitken C">CE Aitken</name></author><author><name sortKey="Lorsch, Jr" uniqKey="Lorsch J">JR Lorsch</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hinnebusch, Ag" uniqKey="Hinnebusch A">AG Hinnebusch</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cho, Pf" uniqKey="Cho P">PF Cho</name></author><author><name sortKey="Poulin, F" uniqKey="Poulin F">F Poulin</name></author><author><name sortKey="Cho Park, Ya" uniqKey="Cho Park Y">YA Cho-Park</name></author><author><name sortKey="Cho Park, Ib" uniqKey="Cho Park I">IB Cho-Park</name></author><author><name sortKey="Chicoine, Jd" uniqKey="Chicoine J">JD Chicoine</name></author><author><name sortKey="Lasko, P" uniqKey="Lasko P">P Lasko</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Morita, M" uniqKey="Morita M">M Morita</name></author><author><name sortKey="Ler, Lw" uniqKey="Ler L">LW Ler</name></author><author><name sortKey="Fabian, Mr" uniqKey="Fabian M">MR Fabian</name></author><author><name sortKey="Siddiqui, N" uniqKey="Siddiqui N">N Siddiqui</name></author><author><name sortKey="Mullin, M" uniqKey="Mullin M">M Mullin</name></author><author><name sortKey="Henderson, Vc" uniqKey="Henderson V">VC Henderson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Villaescusa, Jc" uniqKey="Villaescusa J">JC Villaescusa</name></author><author><name sortKey="Verrotti, Ac" uniqKey="Verrotti A">AC Verrotti</name></author><author><name sortKey="Ferretti, E" uniqKey="Ferretti E">E Ferretti</name></author><author><name sortKey="Farookhi, R" uniqKey="Farookhi R">R Farookhi</name></author><author><name sortKey="Blasi, F" uniqKey="Blasi F">F Blasi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hernandez, G" uniqKey="Hernandez G">G Hernandez</name></author><author><name sortKey="Han, H" uniqKey="Han H">H Han</name></author><author><name sortKey="Gandin, V" uniqKey="Gandin V">V Gandin</name></author><author><name sortKey="Fabian, L" uniqKey="Fabian L">L Fabian</name></author><author><name sortKey="Ferreira, T" uniqKey="Ferreira T">T Ferreira</name></author><author><name sortKey="Zuberek, J" uniqKey="Zuberek J">J Zuberek</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tettweiler, G" uniqKey="Tettweiler G">G Tettweiler</name></author><author><name sortKey="Kowanda, M" uniqKey="Kowanda M">M Kowanda</name></author><author><name sortKey="Lasko, P" uniqKey="Lasko P">P Lasko</name></author><author><name sortKey="Sonenberg, N" uniqKey="Sonenberg N">N Sonenberg</name></author><author><name sortKey="Hernandez, G" uniqKey="Hernandez G">G Hernandez</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Osborne, Mj" uniqKey="Osborne M">MJ Osborne</name></author><author><name sortKey="Volpon, L" uniqKey="Volpon L">L Volpon</name></author><author><name sortKey="Kornblatt, Ja" uniqKey="Kornblatt J">JA Kornblatt</name></author><author><name sortKey="Culjkovic Kraljacic, B" uniqKey="Culjkovic Kraljacic B">B Culjkovic-Kraljacic</name></author><author><name sortKey="Baguet, A" uniqKey="Baguet A">A Baguet</name></author><author><name sortKey="Borden, Kl" uniqKey="Borden K">KL Borden</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bachvaroff, Tr" uniqKey="Bachvaroff T">TR Bachvaroff</name></author><author><name sortKey="Gornik, Sg" uniqKey="Gornik S">SG Gornik</name></author><author><name sortKey="Concepcion, Gt" uniqKey="Concepcion G">GT Concepcion</name></author><author><name sortKey="Waller, Rf" uniqKey="Waller R">RF Waller</name></author><author><name sortKey="Mendez, Gs" uniqKey="Mendez G">GS Mendez</name></author><author><name sortKey="Lippmeier, Jc" uniqKey="Lippmeier J">JC Lippmeier</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hoppenrath, M" uniqKey="Hoppenrath M">M Hoppenrath</name></author><author><name sortKey="Leander, Bs" uniqKey="Leander B">BS Leander</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Goggin, Cl" uniqKey="Goggin C">CL Goggin</name></author><author><name sortKey="Barker, Sc" uniqKey="Barker S">SC Barker</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Reece, Ks" uniqKey="Reece K">KS Reece</name></author><author><name sortKey="Siddall, Me" uniqKey="Siddall M">ME Siddall</name></author><author><name sortKey="Burreson, Em" uniqKey="Burreson E">EM Burreson</name></author><author><name sortKey="Graves, Je" uniqKey="Graves J">JE Graves</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Saldarriaga, Jf" uniqKey="Saldarriaga J">JF Saldarriaga</name></author><author><name sortKey="Mcewan, Ml" uniqKey="Mcewan M">ML McEwan</name></author><author><name sortKey="Fast, Nm" uniqKey="Fast N">NM Fast</name></author><author><name sortKey="Taylor, Fjr" uniqKey="Taylor F">FJR Taylor</name></author><author><name sortKey="Keeling, Pj" uniqKey="Keeling P">PJ Keeling</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gajadhar, Aa" uniqKey="Gajadhar A">AA Gajadhar</name></author><author><name sortKey="Marquardt, Wc" uniqKey="Marquardt W">WC Marquardt</name></author><author><name sortKey="Hall, R" uniqKey="Hall R">R Hall</name></author><author><name sortKey="Gunderson, J" uniqKey="Gunderson J">J Gunderson</name></author><author><name sortKey="Ariztia Carmona, Ev" uniqKey="Ariztia Carmona E">EV Ariztia-Carmona</name></author><author><name sortKey="Sogin, Ml" uniqKey="Sogin M">ML Sogin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Baldauf, S" uniqKey="Baldauf S">S Baldauf</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Burki, F" uniqKey="Burki F">F Burki</name></author><author><name sortKey="Shalchian Tabrizi, K" uniqKey="Shalchian Tabrizi K">K Shalchian-Tabrizi</name></author><author><name sortKey="Minge, M" uniqKey="Minge M">M Minge</name></author><author><name sortKey="Skjaevelenad, A" uniqKey="Skjaevelenad A">A Skjaevelenad</name></author><author><name sortKey="Nikolaev, S" uniqKey="Nikolaev S">S Nikolaev</name></author><author><name sortKey="Jakobsen, Ks" uniqKey="Jakobsen K">KS Jakobsen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bachvaroff, Tr" uniqKey="Bachvaroff T">TR Bachvaroff</name></author><author><name sortKey="Handy, Sm" uniqKey="Handy S">SM Handy</name></author><author><name sortKey="Place, Ar" uniqKey="Place A">AR Place</name></author><author><name sortKey="Delwiche, Cf" uniqKey="Delwiche C">CF Delwiche</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Guillou, L" uniqKey="Guillou L">L Guillou</name></author><author><name sortKey="Viprey, M" uniqKey="Viprey M">M Viprey</name></author><author><name sortKey="Chambouvet, A" uniqKey="Chambouvet A">A Chambouvet</name></author><author><name sortKey="Welsh, Rm" uniqKey="Welsh R">RM Welsh</name></author><author><name sortKey="Kirkham, Ar" uniqKey="Kirkham A">AR Kirkham</name></author><author><name sortKey="Massana, R" uniqKey="Massana R">R Massana</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Coats, Dw" uniqKey="Coats D">DW Coats</name></author><author><name sortKey="Kim, S" uniqKey="Kim S">S Kim</name></author><author><name sortKey="Bachvaroff, Tr" uniqKey="Bachvaroff T">TR Bachvaroff</name></author><author><name sortKey="Handy, Sm" uniqKey="Handy S">SM Handy</name></author><author><name sortKey="Delwiche, Cf" uniqKey="Delwiche C">CF Delwiche</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bachvaroff, Tr" uniqKey="Bachvaroff T">TR Bachvaroff</name></author><author><name sortKey="Handy, Sm" uniqKey="Handy S">SM Handy</name></author><author><name sortKey="Place, Ar" uniqKey="Place A">AR Place</name></author><author><name sortKey="Delwiche, Cf" uniqKey="Delwiche C">CF Delwiche</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tomoo, K" uniqKey="Tomoo K">K Tomoo</name></author><author><name sortKey="Shen, X" uniqKey="Shen X">X Shen</name></author><author><name sortKey="Okabe, K" uniqKey="Okabe K">K Okabe</name></author><author><name sortKey="Nozoe, Y" uniqKey="Nozoe Y">Y Nozoe</name></author><author><name sortKey="Fukuhara, S" uniqKey="Fukuhara S">S Fukuhara</name></author><author><name sortKey="Morino, S" uniqKey="Morino S">S Morino</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mader, S" uniqKey="Mader S">S Mader</name></author><author><name sortKey="Lee, H" uniqKey="Lee H">H Lee</name></author><author><name sortKey="Pause, A" uniqKey="Pause A">A Pause</name></author><author><name sortKey="Sonenberg, N" uniqKey="Sonenberg N">N Sonenberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Altmann, M" uniqKey="Altmann M">M Altmann</name></author><author><name sortKey="Schmitz, N" uniqKey="Schmitz N">N Schmitz</name></author><author><name sortKey="Berset, C" uniqKey="Berset C">C Berset</name></author><author><name sortKey="Trachsel, H" uniqKey="Trachsel H">H Trachsel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, L" uniqKey="Li L">L Li</name></author><author><name sortKey="Hong, R" uniqKey="Hong R">R Hong</name></author><author><name sortKey="Hastings, J" uniqKey="Hastings J">J Hastings</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lasko, P" uniqKey="Lasko P">P Lasko</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lasda, El" uniqKey="Lasda E">EL Lasda</name></author><author><name sortKey="Blumenthal, T" uniqKey="Blumenthal T">T Blumenthal</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jankowska Anyszka, M" uniqKey="Jankowska Anyszka M">M Jankowska-Anyszka</name></author><author><name sortKey="Lamphear, Bj" uniqKey="Lamphear B">BJ Lamphear</name></author><author><name sortKey="Aamodt, Ej" uniqKey="Aamodt E">EJ Aamodt</name></author><author><name sortKey="Harrington, T" uniqKey="Harrington T">T Harrington</name></author><author><name sortKey="Darzynkiewicz, E" uniqKey="Darzynkiewicz E">E Darzynkiewicz</name></author><author><name sortKey="Stolarski, R" uniqKey="Stolarski R">R Stolarski</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Keiper, Bd" uniqKey="Keiper B">BD Keiper</name></author><author><name sortKey="Lamphear, Bj" uniqKey="Lamphear B">BJ Lamphear</name></author><author><name sortKey="Deshpande, Am" uniqKey="Deshpande A">AM Deshpande</name></author><author><name sortKey="Jankowska Anyszka, M" uniqKey="Jankowska Anyszka M">M Jankowska-Anyszka</name></author><author><name sortKey="Aamodt, Ej" uniqKey="Aamodt E">EJ Aamodt</name></author><author><name sortKey="Blumenthal, T" uniqKey="Blumenthal T">T Blumenthal</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dinkova, Td" uniqKey="Dinkova T">TD Dinkova</name></author><author><name sortKey="Keiper, Bd" uniqKey="Keiper B">BD Keiper</name></author><author><name sortKey="Korneeva, Nl" uniqKey="Korneeva N">NL Korneeva</name></author><author><name sortKey="Aamodt, Ej" uniqKey="Aamodt E">EJ Aamodt</name></author><author><name sortKey="Rhoads, Re" uniqKey="Rhoads R">RE Rhoads</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhang, H" uniqKey="Zhang H">H Zhang</name></author><author><name sortKey="Campbell, Da" uniqKey="Campbell D">DA Campbell</name></author><author><name sortKey="Sturm, Nr" uniqKey="Sturm N">NR Sturm</name></author><author><name sortKey="Lin, S" uniqKey="Lin S">S Lin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hearne, Jl" uniqKey="Hearne J">JL Hearne</name></author><author><name sortKey="Pitula, Js" uniqKey="Pitula J">JS Pitula</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhang, S" uniqKey="Zhang S">S Zhang</name></author><author><name sortKey="Sui, Z" uniqKey="Sui Z">Z Sui</name></author><author><name sortKey="Chang, L" uniqKey="Chang L">L Chang</name></author><author><name sortKey="Kang, K" uniqKey="Kang K">K Kang</name></author><author><name sortKey="Ma, J" uniqKey="Ma J">J Ma</name></author><author><name sortKey="Kong, F" uniqKey="Kong F">F Kong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hernandez, G" uniqKey="Hernandez G">G Hernandez</name></author><author><name sortKey="Vazquez Pianzola, P" uniqKey="Vazquez Pianzola P">P Vazquez-Pianzola</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Freire, Er" uniqKey="Freire E">ER Freire</name></author><author><name sortKey="Malvezzi, Am" uniqKey="Malvezzi A">AM Malvezzi</name></author><author><name sortKey="Vashisht, Aa" uniqKey="Vashisht A">AA Vashisht</name></author><author><name sortKey="Zuberek, J" uniqKey="Zuberek J">J Zuberek</name></author><author><name sortKey="Saada, Ea" uniqKey="Saada E">EA Saada</name></author><author><name sortKey="Langousis, G" uniqKey="Langousis G">G Langousis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Freire, Er" uniqKey="Freire E">ER Freire</name></author><author><name sortKey="Vashisht, Aa" uniqKey="Vashisht A">AA Vashisht</name></author><author><name sortKey="Malvezzi, Am" uniqKey="Malvezzi A">AM Malvezzi</name></author><author><name sortKey="Zuberek, J" uniqKey="Zuberek J">J Zuberek</name></author><author><name sortKey="Langousis, G" uniqKey="Langousis G">G Langousis</name></author><author><name sortKey="Saada, Ea" uniqKey="Saada E">EA Saada</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Volpon, L" uniqKey="Volpon L">L Volpon</name></author><author><name sortKey="Osborne, Mj" uniqKey="Osborne M">MJ Osborne</name></author><author><name sortKey="Culjkovic Kraljacic, B" uniqKey="Culjkovic Kraljacic B">B Culjkovic-Kraljacic</name></author><author><name sortKey="Borden, Kl" uniqKey="Borden K">KL Borden</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Grabherr, Mg" uniqKey="Grabherr M">MG Grabherr</name></author><author><name sortKey="Haas, Bj" uniqKey="Haas B">BJ Haas</name></author><author><name sortKey="Yassour, M" uniqKey="Yassour M">M Yassour</name></author><author><name sortKey="Levin, Jz" uniqKey="Levin J">JZ Levin</name></author><author><name sortKey="Thompson, Da" uniqKey="Thompson D">DA Thompson</name></author><author><name sortKey="Amit, I" uniqKey="Amit I">I Amit</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Park, Mg" uniqKey="Park M">MG Park</name></author><author><name sortKey="Cooney, Sk" uniqKey="Cooney S">SK Cooney</name></author><author><name sortKey="Yih, W" uniqKey="Yih W">W Yih</name></author><author><name sortKey="Coats, Dw" uniqKey="Coats D">DW Coats</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bachvaroff, Tr" uniqKey="Bachvaroff T">TR Bachvaroff</name></author><author><name sortKey="Place, Ar" uniqKey="Place A">AR Place</name></author><author><name sortKey="Coats, Dw" uniqKey="Coats D">DW Coats</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sievers, F" uniqKey="Sievers F">F Sievers</name></author><author><name sortKey="Wilm, A" uniqKey="Wilm A">A Wilm</name></author><author><name sortKey="Dineen, D" uniqKey="Dineen D">D Dineen</name></author><author><name sortKey="Gibson, Tj" uniqKey="Gibson T">TJ Gibson</name></author><author><name sortKey="Karplus, K" uniqKey="Karplus K">K Karplus</name></author><author><name sortKey="Li, W" uniqKey="Li W">W Li</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Langmead, B" uniqKey="Langmead B">B Langmead</name></author><author><name sortKey="Trapnell, C" uniqKey="Trapnell C">C Trapnell</name></author><author><name sortKey="Pop, M" uniqKey="Pop M">M Pop</name></author><author><name sortKey="Salzberg, Sl" uniqKey="Salzberg S">SL Salzberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Thorvaldsdottir, H" uniqKey="Thorvaldsdottir H">H Thorvaldsdottir</name></author><author><name sortKey="Robinson, Jt" uniqKey="Robinson J">JT Robinson</name></author><author><name sortKey="Mesirov, Jp" uniqKey="Mesirov J">JP Mesirov</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stamatakis, A" uniqKey="Stamatakis A">A Stamatakis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schmidt, Ha" uniqKey="Schmidt H">HA Schmidt</name></author><author><name sortKey="Strimmer, K" uniqKey="Strimmer K">K Strimmer</name></author><author><name sortKey="Vingron, M" uniqKey="Vingron M">M Vingron</name></author><author><name sortKey="Von Haeseler, A" uniqKey="Von Haeseler A">A von Haeseler</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Vacic, V" uniqKey="Vacic V">V Vacic</name></author><author><name sortKey="Uversky, Vn" uniqKey="Uversky V">VN Uversky</name></author><author><name sortKey="Dunker, Ak" uniqKey="Dunker A">AK Dunker</name></author><author><name sortKey="Lonardi, S" uniqKey="Lonardi S">S Lonardi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Crooks, Ge" uniqKey="Crooks G">GE Crooks</name></author><author><name sortKey="Hon, G" uniqKey="Hon G">G Hon</name></author><author><name sortKey="Chandonia, Jm" uniqKey="Chandonia J">JM Chandonia</name></author><author><name sortKey="Brenner, Se" uniqKey="Brenner S">SE Brenner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kelley, La" uniqKey="Kelley L">LA Kelley</name></author><author><name sortKey="Sternberg, Mj" uniqKey="Sternberg M">MJ Sternberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Humphrey, W" uniqKey="Humphrey W">W Humphrey</name></author><author><name sortKey="Dalke, A" uniqKey="Dalke A">A Dalke</name></author><author><name sortKey="Schulten, K" uniqKey="Schulten K">K Schulten</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Maryland</li></region><settlement><li>Baltimore</li></settlement><orgName><li>Université du Maryland</li></orgName></list><tree><country name="États-Unis"><region name="Maryland"><name sortKey="Jones, Grant D" sort="Jones, Grant D" uniqKey="Jones G" first="Grant D" last="Jones">Grant D. Jones</name></region><name sortKey="Bachvaroff, Tsvetan R" sort="Bachvaroff, Tsvetan R" uniqKey="Bachvaroff T" first="Tsvetan R" last="Bachvaroff">Tsvetan R. Bachvaroff</name><name sortKey="Jagus, Rosemary" sort="Jagus, Rosemary" uniqKey="Jagus R" first="Rosemary" last="Jagus">Rosemary Jagus</name><name sortKey="Jones, Grant D" sort="Jones, Grant D" uniqKey="Jones G" first="Grant D" last="Jones">Grant D. Jones</name><name sortKey="Place, Allen R" sort="Place, Allen R" uniqKey="Place A" first="Allen R" last="Place">Allen R. Place</name><name sortKey="Williams, Ernest P" sort="Williams, Ernest P" uniqKey="Williams E" first="Ernest P" last="Williams">Ernest P. Williams</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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